Most studies suggested that elevated IRTKS expression or the activated fusion gene FGFR3-BAIAP2L1 promoted tumor growth and progression by activating FGFR3 (Nakanishi et al, 2015), epidermal growth factor receptor (EGFR) signaling (Wang et al, 2013), and known membrane protrusions. This evidence concerns the gene BAIAP2L1 and neoplasm.