In our cohort, the prevalence of pathogenic variants on these genes were respectively, 0.006%, 0.080%, and 0.006%, which demonstrated a higher prevalence for GCK-MODY, and lower for HNF1A-MODY and HNF4A-MODY comparing to other cohorts, including UK biobank and Geisinger cohort. Here, GCK is linked to MODY.