The induction of Lgr5 was fairly specific, as other gastric stem cell markers, such as Sox2, Troy, Runx1, Lrig1, and others (Liabeuf et al, 2022) were not induced as a consequence of infection (Fig S1C); an exception was Ascl2, the expression of which mirrored that of Lgr5 (Fig S1C). This evidence concerns the gene LRIG1 and infection.