PPIB and multiple endocrine neoplasia: To assess the roleof linker sequence identity, we first replace the 15-nt linker ofM1TH with the 25-nt linker from the homologous triple helixfound in the multiple endocrine neoplasia-β (MENβ) lncRNA.5 We designate this RNA chimera as M1linkβ (Figure 1B).