To this end, our findings (Figure 1A) of lower FRs in dystonia compared to PD may further substantiate (Starr et al., 2005; Tang et al., 2007) such claims, whereby greater inhibition of GPi would produce decreased inhibitory output, and thus under-inhibition of thalamocortical motor networks, giving rise to hyperkinetic motor symptoms, whereas the opposite would be true in PD (DeLong and Wichmann, 2007). This evidence concerns the gene GPI and Dystonia.