GPI and Parkinson disease: To this end, our findings (Figure 1A) of lower FRs in dystonia compared to PD may further substantiate (Starr et al., 2005; Tang et al., 2007) such claims, whereby greater inhibition of GPi would produce decreased inhibitory output, and thus under-inhibition of thalamocortical motor networks, giving rise to hyperkinetic motor symptoms, whereas the opposite would be true in PD (DeLong and Wichmann, 2007).