Additionally, when these samples from patients with brain metastases were deconvoluted into 30 subtypes, a subtype that was highly enriched in samples from patients with primary NSCLC, with high levels of IFITM3, IFI27, TPM2, and HBG2 reads, was similarly enriched in samples from patients with brain metastases. The gene discussed is TPM2; the disease is non-small cell lung carcinoma.