ALG5 and autosomal dominant polycystic kidney disease: Among the 10%–15% of patients suspected to have ADPKD who have no explaining variants in either PKD1 or PKD2, next-generation sequencing (NGS) has identified several other genes in which variants cause ADPKD, including DNAJB11 (5), GANAB (6), ALG9 (7), and more recently, IFT140 (8) and ALG5 (9).