CD93 and metastatic malignant neoplasm in the lymph nodes: Among all clinicopathological variables evaluated, univariate Cox regression showed that presence of lymph node metastasis (HR = 1.72, P < 0.001), higher depth of tumor invasion (HR = 1.52, P = 0.022), presence of distant metastasis (HR = 14.12, P = 0.009), higher tumor grade (HR = 2.01, P < 0.001), presence of intravascular tumor thrombus (HR = 1.80, P = 0.011), neuron invasion (HR = 1.45, P = 0.033), as well as higher CD93 expression (HR = 3.53, P < 0.001), were significantly associated with poorer overall survival.