CORIN and heart failure: Corin has previously been identified as a cell surface marker for ventricular cell populations (Zhang et al., 2019) and has been reported as being dysregulated (both downregulated and upregulated) in hypertrophy and heart failure (Khoury et al., 2021; Tran et al., 2004; Ichiki et al., 2013; Langenickel et al., 2004).