For distinction between smouldering myeloma and myeloma (requiring therapy) [1], initial workup included laboratory tests investigating myeloma-defining events (CRAB criteria); both the criteria for anemia (Hb < 6.2 mmol/L) and for renal insufficiency (GFR-CKD-epi < 40 ml/min/1.73 m2) were not met [1]. Here, GSTM1 is linked to plasma cell myeloma.