ACVR1 and Anxiety: OFT was performed following the last PWT and TWL tests, the results of OFT showed that intrathecal injection of BMP10 peptide, ALK2-IN-2 did not cause any motor impairment and anxiety-like behavior (Figures 8C–F) (Time in center zone: One-way ANOVA F2,15 = 0.49, P = 0.622; Average speed: One-way ANOVA F2,15 = 0.287, P = 0.754; Total distance: One-way ANOVA F2,15 = 0.463, P = 0.638).