SYNJ1 and Parkinson disease: Similarly, mutations in LRRK2, a protein kinase that phosphorylates SYNJ1 and is involved in endocytosis (Pan et al., 2017; Schechter and Sharon, 2021) and autophagy (reviewed in (Madureira et al., 2020)) have been identified as risk factors for PD (Summarised in Table 1).