NEFL and amyotrophic lateral sclerosis: This study utilized enzyme-linked immunosorbent assay to measure CSF C-X-C motif chemokine ligand 12 levels in healthy controls, amyotrophic lateral sclerosis patients and patients with amyotrophic lateral sclerosis–mimic disorders, assessing its potential as a diagnostic biomarker and comparing it with neurofilament light chain levels.