During NASH, single‐cell profiling also suggested that an abundance of hepatic conventional dendritic cells (cDCs), especially type 1 cDCs expressing chemokine X‐C receptor 1 (XCR1), shows a remarkable increase in the liver and is associated with NASH worsening27 (Figure 3F). This evidence concerns the gene XCR1 and metabolic dysfunction-associated steatohepatitis.