Further correlation analysis between the TMEM229A Q200del mutation and clinicopathological characteristics suggested that a lower frequency of the Q200del mutation was associated with positive lymph node metastasis (p = 0.043), advanced TNM stage (p = 0.035), positive cancer thrombus (p = 0.044), and pathological features (p = 0.008) (Table 1). Here, TMEM229A is linked to cancer.