Results show that tumourigenesis and immune‐related pathways, such as pentose‐phosphate‐pathway, cell cycle pathway, N‐glycan‐biosynthesis, glycolysis‐gluconeogenesis, p53‐signalling‐pathway, notch signalling pathway, TGF‐beta‐signalling‐pathway, pancreatic cancer, thyroid cancer and prostate cancer were significantly enriched in the high‐risk group (Figure 7A). Here, TP53 is linked to Familial prostate cancer.