Thus, the species lost in the Haemophilus‐dominant C2 cluster include Rothia mucilaginosa, which may be anti‐inflammatory, primarily through inhibition of NF‐κB pathway,47 or bioprotective as its levels were diminished in children at risk of asthma,48 which may help Haemophilus influenzae to promote airway inflammation49 through the inhibition of other protective or anti‐inflammatory species. This evidence concerns the gene NFKB1 and asthma.