NRN1 and Wilson disease: In order to explore whether Neuritin plays a role in the Schwann cell demyelination during WD is caused by regulating PI3K/Akt/mTOR pathway, we set up the ex vivo nerve explants model and found that an up‐regulation of PI3K, p‐Akt, p‐mTOR was revealed by western blotting in Neuritin group.