HLA-DRB1 and polyarticular arthritis: On the other hand, DRB1*07, DRB1*04 and DQA1*02, DQA1*03, DQB1*02, DQB1*03 and C*06 alleles were associated with reduced risk in oligoarthritis patients (FDR < 0.05), and DRB1*04, DQA1*03, DQB1*03 alleles were associated with reduced risk in RF-negative polyarthritis patients (FDR < 0.05).