Correction for multiple testing (FDR < 0.05) revealed 3 CpGs and 1 probe in the individual-level analysis of prevalent cases (see Table 2): cg16541931, cg04329510, and cg09378783 were all found associated with CD and annotated to the promoter region of GPR158 (G protein-coupled receptor), the 3′UTR of C5AR1 (complement C5a receptor 1) and to the gene body of EFGR (epidermal growth factor receptor), respectively, while A_19_P00806441, associated to DVL, was annotated to the LOC105370365 RNA gene. This evidence concerns the gene GPR158 and Cowden disease.