Based on 435 melanoma samples, LPAR1 expression strongly correlated with the expression of NF-κB1 (Spearman’s r = 0.23, P = 9.8 × 10−7), DR6 (Spearman’s r = 0.33, P = 1.9 × 10−12) and IL-10 (Spearman’s r = 0.21, P = 1.3 × 10−5) (Fig. 4). Here, TNFRSF21 is linked to melanoma.