Additionally, in agreement with the results obtained with the B16-OVA model, the numbers of tumor-infiltrating CD45+, granzyme B- or IFNγ-producing CD8+ T cells and CD4+ T cells were significantly greater in the TOFA-treated Th9 group than in the untreated Th9 cell group (Fig. 6G, H and Supplementary Fig. 6h, i). The gene discussed is CD8A; the disease is neoplasm.