MYC and acute myeloid leukemia: Previous studies have demonstrated that BRG1 regulates c-Myc expression by binding to the c-Myc enhancer in AML [19], and our Chromatin immunoprecipitation (ChIP) followed by next-generation sequencing (ChIP-seq) assay also supported that the binding peak of BRG1 was located at the Myc promoter region (Fig. S5A).