ADAM10 and Alzheimer disease: Our bulk neuron model identified a different outlier variant rs395601 near ADAM10 (-2.49 s.d. from 0, FDR q = 2.2 × 10−1,nominal p-value = 1.3 × 10−2), which suggests that different variants may contribute to immune-specific and brain-specific effects of ADAM10 gene expression on AD.