Autoantibodies implicated in inflammatory myopathy (MDA5), systemic sclerosis (Scl-70, PM/Scl-75), and systemic lupus erythematosus [SLE; KU(P70/P80), ssDNA] were particularly enriched in NP when compared with CC or HC and were most highly elevated at visit 2 postboost (Fig. 2B, 2C). This evidence concerns the gene IFIH1 and systemic sclerosis.