Next, correlation analysis based on tumor area revealed a positive correlation between fibrosis and intra- and extra-tumoral αSMA expression (correlation coefficients 0.638 and 0.549, respectively), but a negative correlation with intra- and extra-tumoral GFAP expression (correlation coefficients -0.476 and -0.354, respectively) (Fig. 5h, i). Here, ACTA1 is linked to neoplasm.