The gait performance assay, which was assessed by analyzing the footprint pattern of mice while walking along a narrow corridor of catwalk equipment (Xu et al., 2019), revealed that HD KI mice expressing cytoplasmic TDP‐43 lacked a normal, uniform, alternating left–right step pattern as compared with the control HD KI mice receiving the control AAV injection or WT mice injected with AAV‐ΔNLS‐TDP‐43 (Figure 3f). Here, TARDBP is linked to Huntington disease.