Several blood biomarkers, such as plasma Aβ42, Aβ42/40 ratio, p-tau, t-tau, neurofilament light polypeptide (NfL), glial fibrillary acidic protein (GFAP), and soluble triggering receptor expressed on myeloid cells 2 (sTREM2), have been identified as potential biomarkers for AD (Tao et al., 2023). The gene discussed is NEFL; the disease is Alzheimer disease.