We selected 131 and 75 SNPs as instrumental variables for two different hypothyroidism datasets, 632 SNPs for 26 proteins (including 21 SNPs for the CXCL10 external validation dataset), 45 SNPs for TSH, 24 SNPs for FT4, 4 SNPs for TPOAB concentration, and 23 SNPs for IPF (Supplementary Table 1). This evidence concerns the gene CXCL10 and idiopathic pulmonary fibrosis.