TRIM21 and autoimmune disease: Interestingly, autoAbs to small nuclear ribonucleoprotein, Sjögren’s-syndrome-related antigen A (Ro/SSA), Jo-1, and synthetase syndrome (PL)-7 which are normally detected in SLE and other autoimmune diseases (54), were also identified in high levels in the plasma of the control mice and were depleted after BAFF neutralization.