Furthermore, a current publication developed a support vector machine (SVM) model by combining IFN-gamma with TNF-alpha, IL-6, and IL-10, measuring serum levels of these four cytokines, which held a potential as biomarker for diagnosing TB with an AUC of 0.850, a sensitivity of 0.850 and specificity of 0.780 (101). The gene discussed is TNF; the disease is tuberculosis.