Similarly, the plasma levels of MPO-DNA complex in patients with o-JIA [0.1356 (IQR: 0.0961-0.1806)], p-JIA [0.1295 (IQR: 0.09540-0.0.2485)] and ERA [0.1823 (IQR:0.08975-0.5570)] were higher than those in HCs [0.0797 (IQR:0.05125-0.1500)] (p = 0.0163, p = 0.0302 and p = 0.0258, respectively; Figure 2B), these results verified that excessive NET formation were present in peripheral blood of JIA patients. This evidence concerns the gene MPO and juvenile idiopathic arthritis.