TNF and juvenile idiopathic arthritis: As shown in Figures 1A, B, the percentages of the NET-occupied area were markedly greater in JIA-derived neutrophils than in HC-derived neutrophils after no stimulation (28.75 ± 1.355% vs. 21 ± 2.236%, p = 0.0065), PMA stimulation (53.4 ± 2.172% vs. 40.5 ± 2.527%, p = 0.0021) or TNF-α stimulation (44.83 ± 2.628% vs. 34 ± 3.215%, p = 0.0247).