HLA-DQA1 and type 1 diabetes mellitus: For HLA class II alleles, those which were part of the HLA DQ2 and DQ8 haplotypes of predisposition to T1D were more frequent in CH T1D subjects than in NCH subjects, i.e., HLA-DRB1*03:01:01 (44.5% vs. 0%, p-value < 0.0001), DRB1*04:01:01 (12.5% vs. 0%, p-value = 0.03); HLA-DQA1*03:01:01 (28% vs. 7%, p-value = 0.01), HLA-DQA1*05:01:01 (45.5% vs. 0%, p-value < 0.0001); HLA-DQB1*02:01:01 (45.5% vs. 7%, p-value < 0.0001) and HLA-DQB1*03:02:01 (30% vs. 3%, p-value = 0.0005).