CCL4 and mood disorder: In the Ant -Ins, we found three downregulated DEGs that recapitulated our mood disorder vs. control findings (see Table 3), including the protein synthesis PSK5 gene and ATP-binding heat shock protein HSPA7 gene (Pantazatos et al. 2017), and a mitogen-inducible monokine called C-C motif chemokine ligand-4 immunoregulatory and inflammatory CCL4 gene (Table 3A; Fig 3A–B).