P. falciparum erythrocyte membrane protein 1 on erythrocytes binds to endothelial cell surface proteins, such as intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1, and a cluster of differentiation 36 (CD36), causing cytoadherence and sequestration, which is the mechanism underlying cerebral malaria [10]. The gene discussed is ICAM1; the disease is cerebral malaria.