Agreeing to our results, it has been concluded that the level of p53 was more common to be increasing in T3/T4 lesions than T1/T2 in MF/SS (Sézary syndrome) [24], high in nephroblastoma/Wilms' tumor and much higher in anaplastic cases [34], and then in breast tumor/benign carcinoma [35]. This evidence concerns the gene TP53 and Sezary syndrome.