Figure 2 shows a 5-generation family tree based on interviews with the patient and their family. III-2 is the index case. FH mutations were found in III-1 and III-3, who are his siblings. Furthermore, UL and kidney disease were both identified in the maternal aunts of the patients (II-5, 6), although the specific details are unknown. IV-1 and IV-2, who are the children of III-1, were diagnosed with UL at 30 and 35 years old, respectively, but have not yet undergone FH testing (Fig. 2). Hence, we will perform abdominal MRI for these FH mutation carriers annually to screen for renal cancer. This evidence concerns the gene FH and renal carcinoma.