ALK and cancer: Similarly, ATP‐binding site mutation (ALK‐G1269A) and near αC helix site mutations (ALK‐C1156Y, ALK‐L1152R, ALK‐F1174C, and ALK‐1151T insertion) were identified in ALK‐rearranged cancers, conferring resistance by causing conformational changes.87, 126, 127, 128