In RA patients, the levels of mEPCR on NK cells, non-classic monocytes, CD3+, CD3+CD4+ and CD3+CD8+ T cells were inversely correlated to 66/28SJC, 28/68 TJC and/or DAS28-CRP scores (rho < −0.35 indicated significant correlations) (Fig. 4A). Here, CD4 is linked to rheumatoid arthritis.