In patients with PCOS, it is possible to find an increase in dehydroepiandrosterone sulfate (DHEAS), luteinizing hormone (LH) follicle stimulating hormone (FSH) ratio, total testosterone, homeostatic model assessment of insulin resistance (HOMA-IR) and anti-Müllerian hormone (AMH) levels (Sumbul et al., 2022). Here, PLOD1 is linked to Insulin resistance.