KANSL1 and Alzheimer disease: KANSL1 plays a crucial role in regulating mitophagy and is a novel gene for drug targeting in PD.65 However, we were unable to identify a potential causal SNP for many GWAS loci across different neurodegenerative conditions, perhaps because the SNPs were not identified among the shared genetic etiology of multiple neurodegenerative disorders,66 and the observed disease-related peaks were observed only in PD and AD shared genetic loci.