SEZ6L2 is a brain-specific receptor-like protein, whose overexpression can predict poor prognosis in cancer patients.64 We found a potential causal SNP rs62056801 for both AD and PD GWAS loci, which may affect KANSL1 expression by increasing the cCRE chromatin accessibility in AD/ADRD cerebellum. The gene discussed is SEZ6L2; the disease is cancer.