These include genes involve in cellular signaling such as regulator of G protein signaling 16 (RGS16) and interleukin 13 receptor subunit alpha 2 (IL13RA2), cell differentiation genes such as ectopic viral integration site 2B (EVI2B), and the innate immune response genes to viral infection like 2’−5’-oligoadenylate synthetase 2 (OAS2). The gene discussed is IL13RA2; the disease is viral infectious disease.