Comparing ARNT2 mRNA levels in tumor and normal tissues from the TCGA and GTEx database, we found that ARNT2 levels were elevated in several cancer types including breast invasive carcinoma (BRCA), pancreatic adenocarcinoma (PAAD), and skin cutaneous melanoma (SKCM) (Figure S2A). The gene discussed is ARNT2; the disease is invasive breast carcinoma.