In our study, the CSGs with the highest number of P/LP variants in cases versus controls included ELP1 and SUFU. The prevalence of P/LP variants in ELP1 in our cases (3.1%, 5/160) was similar to what has previously been reported in a large cohort of cases with medulloblastoma (3.2%, 23/713) (16). The gene discussed is ELP1; the disease is medulloblastoma.