Kaplan-Meier analysis revealed significantly worse 5-year progression-free survival associated with a strong expression of MAGEA3 (36) LCN2/MMP-9 pathway has been associated with an aggressive phenotype of bladder cancer and the elevated NPV of this protein complex makes them candidate markers of exclusion test for bladder cancer (37). The gene discussed is MMP9; the disease is urinary bladder carcinoma.