Although the above research did not explicitly elucidate the interaction between mitophagy and glycolysis, another study found that activation of Parkin-mediated mitophagy could prevent TGF-β1-mediated FB proliferation and MFB activation by attenuating FB glycolysis process, thus inhibiting fibrosis in IPF (Wang W. et al., 2023). This evidence concerns the gene PRKN and idiopathic pulmonary fibrosis.