CGAS and metabolic dysfunction-associated steatotic liver disease: Mechanistically, bacterial extracellular vesicles (bEVs) released by the gut microbiota induce inflammation and fibrosis in NAFLD by activating cGAS-STING signalling, suggesting that the gut microbiota and bEVs are crucial for the pathogenesis and development of NAFLD and are new targets for the treatment of NAFLD [82].