Oroxylin A stimulates cGAS-STING pathway to enhance the secretion of cytokines such as IFNβ, leading to upregulation of NCOA4 and subsequent regulation of ferritinophagy, indicating that the cGAS-STING pathway regulation of HSC senescence is a potential target for liver fibrosis therapy [43]. This evidence concerns the gene CGAS and Hepatic fibrosis.