DNM2 and neoplasm: Previous studies have suggested that the aggregation of S–S bonds in the mitochondria modulates tumor advancement.[22] Disulfidptosis is a type of cell death triggered by S–S bond stress, which is characterized by the collapse of cytoskeletal proteins and F-actin due to the intracellular accumulation of disulfides.[9] This discovery could eventually offer new avenues for cancer therapy.