However, as a component of the innate immune system, CRP has been regarded as a valuable inflammatory marker in cardiovascular disease, chronic hepatitis, and so on.[29] A systematic evaluation of 271 articles showed that high CRP was associated with higher mortality and poor treatment response in 90% of patients with primary solid tumors.[30] In clinical practice, it is still prudent for healthcare professionals to consider changes in CRP during treatment for patients’ safety. Here, CRP is linked to cardiovascular disorder.