The antitumor drug paclitaxel (PTX) has been established as an effective treatment for various cancers.[17] However, the resistance of tumors to PTX significantly impacts its clinical efficacy.[18] Zhang S[19] collected tissue samples from esophageal cancer (EC) patients and conducted measurements on a range of lncRNAs, including DDX11-AS1. The gene discussed is DDX11; the disease is cancer.