While only biallelic mutations in the KCNJ16 gene appeared disease causing, we included the KCNJ16+/− clone to investigate whether monoallelic mutations in KCNJ16 may express a tubulopathy phenotype as well, which could provide insight into whether carriers of KCNJ16 mutations are at risk of developing kidney disease. Here, KCNJ16 is linked to kidney disorder.